Unraveling the Chemical Properties of A-PVP: A Comprehensive Analysis
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Unraveling the Chemical Properties of A-PVP: A Comprehensive Analysis


Alpha-Pyrrolidinopentiophenone (A-PVP), a synthetic cathinone compound, has garnered significant attention due to its stimulant effects and potential for misuse. Understanding its chemical properties is essential for elucidating its pharmacological actions and addressing associated public health concerns.

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Chemical Identity:

  • Chemical Name: Alpha-Pyrrolidinopentiophenone (A-PVP)
  • Molecular Formula: C15H21NO
  • Chemical Structure:
  • Synonyms: Flakka, gravel, alpha-PVP, α-PVP

Physical Properties:

  • Appearance: A-PVP typically presents as a white to off-white crystalline powder or fine crystals.
  • Melting Point: The melting point of A-PVP falls within a range of approximately 148-149°C.
  • Boiling Point: A-PVP undergoes decomposition upon heating, and a precise boiling point is challenging to determine.
  • Solubility: It is moderately soluble in water and exhibits better solubility in organic solvents such as ethanol and acetone.

Chemical Properties:

  • Stability: A-PVP is relatively stable under ambient conditions but may degrade upon exposure to heat, light, or moisture.
  • Reactivity: It undergoes chemical transformations under acidic or basic conditions and is susceptible to oxidation and reduction reactions.
  • Acid-Base Behavior: A-PVP exhibits basic properties due to the presence of a nitrogen atom in its molecular structure.

Pharmacological Effects:

  • Stimulant Activity: A-PVP acts as a potent central nervous system stimulant, producing effects similar to other cathinone derivatives such as methamphetamine and MDMA.
  • Psychological Effects: Users may experience euphoria, increased alertness, agitation, and hallucinations upon consuming A-PVP.
  • Toxicity: Prolonged or high-dose use of A-PVP can lead to adverse effects such as cardiovascular issues, psychosis, and addiction.

Legislative Status and Regulation:

  • A-PVP is classified as a Schedule I controlled substance in many jurisdictions due to its high abuse potential and lack of accepted medical use.
  • Regulatory agencies monitor and control the production, distribution, and sale of A-PVP to prevent its misuse and associated harm.


A-PVP, a synthetic cathinone with stimulant properties, poses significant risks to public health due to its potential for abuse and associated adverse effects. Further research into its pharmacological mechanisms and toxicological profile is necessary to develop effective prevention and intervention strategies. Regulatory measures aimed at restricting its availability and educating the public about its risks are crucial for mitigating the harm associated with A-PVP misuse.Information for preparing this article was taken from the site: https://en.wikipedia.org/wiki/Alpha-Pyrrolidinopentiophenone

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